{"product_id":"omegagevity-spm","title":"OMEGAgevity™ SPM+","description":"\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eHerring Caviar Oil with Bioactive SPMs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRESOLVE • REPAIR • RESTORE*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOMEGAgevity™ SPM+ is an advanced marine lipid formula designed to support the body’s natural resolution pathways—the active biological processes that help bring an inflammatory response to completion and support the return toward homeostasis.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUnlike conventional omega-3 formulas focused primarily on delivering EPA and DHA, OMEGAgevity™ SPM+ provides a\u003cstrong\u003e \u003c\/strong\u003e\u003c\/span\u003ephospholipid-rich herring caviar marine lipid matrix with SPM pathway intermediates and bioactive Specialized Pro-Resolving Mediators (SPMs).\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis multi-layered approach provides nutritional support at multiple points along the body’s natural pro-resolving lipid pathways.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eINFLAMMATION IS ONLY HALF THE STORY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAn inflammatory response is designed to have a beginning—and an end.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFor years, nutritional strategies have focused largely on influencing the initiation and intensity of inflammation. Research into \u003c\/span\u003eresolution biology\u003cspan\u003e has expanded that understanding.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eResolution is not simply the passive disappearance of inflammatory signals. It is an actively regulated biological program that helps coordinate the transition from an inflammatory response back toward homeostasis.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSpecialized Pro-Resolving Mediators, or\u003cstrong\u003e \u003c\/strong\u003e\u003c\/span\u003eSPMs\u003cspan\u003e, are lipid-derived signaling molecules involved in this process.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThey participate in pathways associated with limiting further inflammatory-cell recruitment, supporting cellular cleanup and helping coordinate tissue repair and restoration.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOMEGAgevity™ SPM+ was designed around this next level of omega-3 biology.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eTHREE LEVELS OF RESOLUTION SUPPORT*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e1 | PHOSPHOLIPID-RICH MARINE LIPID MATRIX\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOMEGAgevity™ SPM+ begins with a naturally complex herring caviar marine lipid matrix.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUnlike conventional fish oils in which omega-3 fatty acids are commonly delivered predominantly as triglycerides, herring caviar provides marine omega-3s within a \u003c\/span\u003ephospholipid-rich matrix.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePhospholipids are structural components of cell membranes, providing a biologically relevant lipid environment for EPA, DHA, and downstream lipid-mediator pathways.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e2 | SPM PATHWAY INTERMEDIATES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eEPA and DHA can be enzymatically transformed into oxygenated lipid intermediates that sit along pathways leading toward specialized pro-resolving mediators.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOMEGAgevity™ SPM+ provides\u003cstrong\u003e \u003c\/strong\u003e\u003c\/span\u003enine identified SPM pathway intermediates\u003cspan\u003e, including 18-HEPE, 17-HDHA, and 14-HDHA.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThese compounds represent multiple points along EPA- and DHA-derived pro-resolving pathways.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e3 | BIOACTIVE SPMs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOMEGAgevity™ SPM+ also provides\u003cstrong\u003e \u003c\/strong\u003e\u003c\/span\u003efive identified bioactive SPMs\u003cspan\u003e from the resolvin, maresin, and protectin families.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTogether, the phospholipid-rich marine matrix, pathway intermediates, and downstream mediators create a comprehensive resolution-focused lipid profile.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eMORE THAN PREFORMED SPMs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe emerging science behind herring roe lipids makes OMEGAgevity™ SPM+ particularly compelling.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA 2026 study published in the \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eJournal of Lipid Research\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e investigated phospholipid-rich herring roe lipids in human-derived macrophages and a keratinocyte\/fibroblast coculture.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eResearchers observed \u003c\/span\u003ebroad SPM biosynthesis\u003cspan\u003e, including prominent increases in E-series resolvins and increases in DHA-derived pro-resolving mediators under the experimental conditions.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eImportantly, the findings were consistent with \u003c\/span\u003enew cellular SPM biosynthesis\u003cspan\u003e, rather than simply the transfer of SPMs already present in the herring roe oil.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e\u003cspan\u003eThis suggests herring roe lipids may also support the body’s own SPM production, adding a fourth layer beyond the three above.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eWHY PHOSPHOLIPIDS MATTER\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe form in which marine omega-3s are delivered may influence how they behave in the body.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn a randomized crossover human study involving 32 adults, phospholipid-rich herring roe oil was compared with triglyceride-rich fish oil.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFollowing an acute dose, plasma phosphatidylcholine exposure to EPA, DHA, and EPA+DHA was significantly higher with the herring roe oil. After two weeks, both sources increased fasting plasma phosphatidylcholine omega-3 levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eResearchers concluded that phospholipid-rich herring roe oil was a \u003c\/span\u003ewell-tolerated and bioavailable source of long-chain omega-3 fatty acids.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis human research supports the biological rationale for the phospholipid-rich herring caviar matrix used in OMEGAgevity™ SPM+.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-pm-slice=\"1 3 []\"\u003e\u003cstrong\u003eDESIGNED TO SUPPORT*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eHealthy resolution pathways\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eA balanced inflammatory response\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eCellular cleanup and restoration\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eTissue repair and recovery pathways\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eHealthy aging\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eMusculoskeletal and joint wellness\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eCardiometabolic wellness\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eSkin and barrier health\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eTHE OMEGAGEVITY™ SPM+ PROFILE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e1.5 g ACTIVE MARINE PHOSPHOLIPID CONCENTRATE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003ePer 3-softgel serving\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSPM PATHWAY INTERMEDIATES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEPA-Derived\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e15-HEPE • 18-HEPE • 15-HpEPE • 5-HpEPE\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eDHA-Derived\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e7-HDHA • 10-HDHA • 14-HDHA • 17-HDHA • 17-HpDHA\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBIOACTIVE SPMs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMaR1\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e — Maresin 1\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eMaR2\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e — Maresin 2\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eRvD5\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e — Resolvin D5\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eRvE2\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e — Resolvin E2\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eNPDx\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e — Neuroprotectin Dx\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eTHE HEALTHGEVITY DIFFERENCE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRESOLUTION-FOCUSED\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDesigned around the biology involved in bringing an inflammatory response toward completion—not simply influencing its initiation.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMULTI-LAYERED APPROACH\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThree levels of resolution support in one formula.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHERRING CAVIAR PHOSPHOLIPIDS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA distinctive marine lipid source providing omega-3 fatty acids within a naturally phospholipid-rich matrix.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHUMAN BIOAVAILABILITY RESEARCH\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePhospholipid-rich herring roe oil has been evaluated in human research and demonstrated bioavailability of long-chain omega-3 fatty acids.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEMERGING 2026 SPM SCIENCE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eHuman-derived cellular research demonstrates that herring roe lipids can promote the biosynthesis of specialized pro-resolving mediators, expanding the scientific rationale beyond the preformed SPM content of the oil.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eContains: Fish (Herring)\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"text-align: center;\"\u003e\u003ca href=\"https:\/\/healthgev.com\/pages\/omegagevity%E2%84%A2-spm-references\"\u003e\u003cstrong\u003eClick here for references \u003c\/strong\u003e\u003c\/a\u003e\u003c\/h3\u003e","brand":"Healthgevity","offers":[{"title":"Default Title","offer_id":52114856640758,"sku":null,"price":94.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/5287\/5766\/files\/OMEGAgevityjar.png?v=1793714241","url":"https:\/\/healthgev.com\/en-ca\/products\/omegagevity-spm","provider":"Healthgevity","version":"1.0","type":"link"}