Colostrum-GI Bio-Biotic™

Healthgevity Exclusive.

Inspired by Human Breast Milk. Engineered for Adult Physiology. 

Most gut health products add bacteria. Colostrum-GI Bio-Biotic™ optimizes the environment those bacteria need to thrive.*

Probiotics introduce beneficial microorganisms. Prebiotics feed them. Postbiotics deliver their byproducts. All three approaches work at the level of the microbiome itself.

Colostrum-GI Bio-Biotic™ works differently — and earlier. MaolactinGI™ Pro is the first bio-biotic protein system designed to support gut health at its foundation: repairing and strengthening the intestinal barrier, addressing micro-inflammation within the gut epithelium, and creating the gut environment in which beneficial bacteria can genuinely thrive.*

Clinically studied in a double-blind, randomized, placebo-controlled human trial. Confirmed in a separate home use evaluation of 100 participants. Effective at 620 mg per serving.*

WHAT IS A "BIO-BIOTIC"?

Beyond Prebiotics, Probiotics and Postbiotics — A New Category

The supplement industry has long defined gut health support in three categories: prebiotics (feeding bacteria), probiotics (adding bacteria), and postbiotics (delivering bacterial byproducts). Each works at the level of the microbiome population.

Maolac introduced a fourth category: the bio-biotic — a precision protein system that works at the gut barrier level, addressing the structural and inflammatory environment that determines whether the gut microbiome can function properly in the first place.*

MaolactinGI™ harnesses the same category of biofunctional proteins that human breast milk uses to build and fortify a newborn's gut barrier — selected by AI from bovine colostrum for their ≥95% structural and functional similarity to human milk proteins, and concentrated for adult physiology.*

The focus is not simply on adding more bacteria. It is on optimizing the gut environment so they — can thrive.*

THE SCIENCE: HOW MAOLACTINGI™ PRO WORKS

Three Mechanisms. One Integrated Gut Support System.*

MaolactinGI™ Pro supports gut health through three interconnected mechanisms — addressing root-level factors that generic colostrum and probiotic supplementation cannot reach.*

Mechanism 1 — Intestinal Barrier Repair and Strengthening MaolactinGI™ Pro delivers biofunctional proteins that support tight junction integrity and epithelial resilience — the physical barrier layer that separates the gut lumen from the bloodstream.* When this barrier is compromised, immune activation, inflammatory signaling, and microbiome disruption follow. By supporting barrier repair and strengthening, MaolactinGI™ Pro addresses one of the most foundational determinants of gut and systemic health.*

Mechanism 2 — Micro-Inflammation Modulation MaolactinGI™ Pro works to address micro-inflammation within the gut epithelium — the low-grade, chronic inflammatory environment that disrupts barrier function and creates conditions unfavorable for beneficial bacteria.* By supporting a more balanced inflammatory environment within the gut wall, it elevates the pH conditions associated with beneficial bacterial activity and microbiome diversity.*

Mechanism 3 — Microbiome Environment Optimization By supporting barrier integrity and reducing epithelial micro-inflammation, MaolactinGI™ Pro creates the internal environment in which beneficial bacteria — including Bifidobacterium species — can establish, diversify, and produce short-chain fatty acids associated with gut and immune health. This approach works upstream of probiotic supplementation, making it an ideal foundation for any gut health protocol.

WHY MAOLACTINGI™ PRO IS NOT STANDARD COLOSTRUM

7x More Effective Than Generic Bovine Colostrum.*

Standard bovine colostrum delivers a broad spectrum of proteins — but they are calibrated for calf physiology, not human adult biology. The IgG antibody profile and protein composition of conventional colostrum are not optimized for the human immune system or gut barrier.*

Maolac's MaolactinGI™ Pro takes a fundamentally different approach. Rather than using whole colostrum, it uses Maolac's Maoreka™ AI platform to screen over 1,500 proteins in human breast milk — mapping their 3D folding structure, functional motifs, receptor interaction domains, and bioactive signaling potential — and then identifies the specific proteins within bovine colostrum that meet a threshold of ≥95% structural and functional biosimilarity.*

The result: a concentrated protein system the body recognizes and uses the way it was designed to — not an approximation of human milk biology, but a precise selection of its most functional components.*

In comparative testing, this formulation demonstrated 7x greater efficacy in supporting healthy inflammatory response balance compared to standard bovine colostrum.*

MaolactinGI™ was recognized as a 2025 WholeFoods Magazine Natural Choice Award winner — an independent industry validation of its innovation and efficacy.*

What the Research Shows*

MaolactinGI™ has been evaluated in a randomized, double-blind, placebo-controlled human pilot study in generally healthy adults — conducted at clinical sites in Australia and Israel.*

Study outcomes included:*

• Support for overall gastrointestinal comfort and function*
• Improvements in digestive-related quality-of-life measures*
• Support for healthy bowel regularity*
• Reduction in occasional bloating*
• Early benefits observed within weeks, with continued support over time*
• Promotion of microbial diversity associated with gut health*
• Support for beneficial bacteria involved in short-chain fatty acid production*

Home Use Evaluation (n=100, 4 weeks):*

• 36% improvement in digestive function scores*
• 70% of participants reported improved bloating support*
• 60% reported reduced abdominal discomfort*
• 65% reported improved regularity*
• 75% reported overall quality-of-life improvement*

Effective clinical dose: 330–620 mg per serving. Colostrum-GI Bio-Biotic™ delivers 620 mg MaolactinGI™ Pro per serving — the higher end of the clinically studied range.*

LPPDS™ — Lipid Proteo-Protective Delivery System

Biofunctional proteins are fragile. The digestive environment — stomach acid, proteolytic enzymes, temperature fluctuation — can degrade protein structure before active fractions reach the intestinal wall where they are needed.

bioREPAIR™ protects both Maolactin systems using LPPDS™ (Lipid Proteo-Protective Delivery System) — a proprietary microencapsulation technology that shields protein structure and function through the full digestive journey. It maintains protein bioactivity, supports intestinal transport, and ensures that the biofunctional proteins arrive intact where they are designed to act.*

THE SIX PROTEIN CLASSES IN MAOLACTIN™

What Makes These Proteins Biologically Active

The Maolactin™ systems contain six categories of functionally significant proteins — each selected for a specific role in human physiology:

1. IgG-like Domain Proteins (IGLDCPs) Proteins characterized by immunoglobulin-like structural domains involved in immune signaling, cell adhesion, and molecular recognition. They support immune homeostasis and cellular communication pathways.* [Click here for detailed scientific explanation →]
2. Glycoproteins Proteins with carbohydrate molecules attached, critical for immune system modulation, cell-to-cell communication, and protein stability. Many naturally occurring hormones, enzymes, and antibodies are glycoproteins.* [Click here for detailed scientific explanation →]
3. Structural Proteins (Actin, Keratins, Vimentin) Proteins that provide mechanical support to cells and tissues, contributing to integrity, shape, and structural resilience. Essential to skin, connective tissue, and cellular scaffolding maintenance.* [Click here for scientific explanation of Actin →] [Click here for scientific explanation of Keratins and Vimentin →]
4. Thioredoxin A small protein central to cellular redox balance — protecting cells from oxidative stress by reducing other proteins through cysteine residue activity. Involved in DNA synthesis, cellular repair, and regulation of cell growth.* [Click here for detailed scientific explanation →]
5. Cathelicidin A family of antimicrobial peptides that form part of the body's innate immune defense — disrupting microbial membrane integrity while also modulating inflammation and supporting tissue recovery signaling.* [Click here for detailed scientific explanation →]
6. Cathepsins Proteolytic enzymes essential for cellular turnover, autophagy, immune function, and tissue remodeling — supporting the normal maintenance processes that keep cells functioning efficiently.* [Click here for detailed scientific explanation →]

POWERED BY MAOLAC

Healthgevity & Maolac — First Global Practitioner-Channel Partnership

Maolac is a biotechnology company pioneering a new category of biofunctional proteins using AI, computational biology, and proteomic science to identify proteins with high biosimilarity to those naturally found in human breast milk.

Winner of the NutraIngredients Start-Up Award 2024, Maolac's Maoreka™ AI platform has analyzed thousands of proteins to develop precision formulations designed to support gut health, immune resilience, recovery, and healthy aging — with a focus on human biological compatibility that conventional colostrum supplementation does not achieve.

Healthgevity is Maolac's first global practitioner-channel partner — bringing both MaolactinGI™ and MaolactinFMR™ to healthcare providers in a single advanced formula. These ingredients are not available in retail supplements at the clinical concentrations and delivery standard used in Colostrum-GI Bio-Biotic™*

Can't decide when to use this vs. bioREPAIR? 

• Colostrum-GI Bio-Biotic™ → foundational support for gut health and digestive function†
• bioREPAIR → advanced support for the gut–muscle axis, recovery, and systemic resilience†

ALLERGEN NOTICE

This product contains dairy (bovine colostrum-derived ingredients).