Rejuvenate (Senolytic)

Rejuvenate — Advanced Senolytic & Cellular Renewal Support

Target the Biology of Aging, Naturally

Rejuvenate  represents the next generation of senotherapeutic nutrition — a precision-formulated blend of clinically studied nutrients that help the body renew, protect, and revitalize cells at the source of aging.
This once-weekly, high-intensity pulse formula was designed to support the body’s natural ability to clear senescent cells, modulate the senescence-associated secretory phenotype (SASP), and stimulate autophagy — the process of cellular renewal and self-cleaning.

Featured Benefits

• Supports the body’s natural clearance of senescent cells*

• Helps maintain healthy inflammatory signaling associated with “inflammaging”*

• Promotes autophagy and cellular rejuvenation*

• Encourages mitochondrial health and energy metabolism*

• Helps protect cells against oxidative stress and environmental damage*

• Supports muscle performance, recovery, and resilience*

• Enhances nutrient bioavailability for optimal cellular uptake*

Mechanistic Focus

Rejuvenate works through two synergistic mechanisms:

1. Senolytic Support: helps the body identify and remove senescent cells that may accumulate with age.*

2. SASP Modulation: supports balanced cellular signaling to maintain a healthy tissue environment.*

Key Ingredients

Fisetin

A naturally occurring polyphenol found in strawberries and apples, Fisetin is among the most researched natural senolytic compounds. It supports cellular protection, antioxidant defense, and balanced aging pathways by helping maintain the body’s ability to manage oxidative stress and senescent cell burden.

Quercetin Phytosome®

Quercetin is a potent flavonoid with broad antioxidant and immune-supportive activity. The Phytosome® form enhances bioavailability up to 20-fold, ensuring effective delivery. Quercetin supports cellular defense, inflammatory balance,and vascular integrity—key components of healthy longevity.

Spermidine (Puremidine®) 

Spermidine is a naturally produced polyamine that supports autophagy, cellular renewal, and metabolic efficiency. It plays a crucial role in maintaining cellular homeostasis, cognitive vitality, and immune balance, supporting longevity through its ability to encourage cellular clean-up and rejuvenation processes.

Senactiv® (Panax notoginseng & Rosa roxburghii)

Senactiv® combines two botanical extracts shown to promote cellular turnover and muscle recovery. By supporting the body’s natural clearance of aged muscle cells and encouraging mitochondrial energy production, Senactiv® helps enhance endurance, improve post-exercise recovery, and *maintain youthful muscle performance.

L-Ergothioneine (MitoPrime®)

Ergothioneine is a rare amino acid found in mushrooms and concentrated in mitochondria, where it supports DNA integrity and oxidative-stress defense.
Emerging research suggests it plays a central role in cellular protection, telomere maintenance, and longevity signaling.

TurmiPure GOLD® & CurcuPrime® (Tetrahydrocurcumin)

This dual turmeric complex combines two clinically advanced forms for maximum bioavailability and cellular activity.
TurmiPure GOLD® delivers 24× better absorption of curcuminoids for healthy inflammatory balance, while CurcuPrime® provides tetrahydrocurcumin—the active metabolite that supports cellular detoxification, antioxidant defense, and SASP modulation.

Apigenin & Luteolin

Two synergistic plant flavonoids known for their ability to neutralize free radicals and support NAD⁺ preservation. Apigenin helps maintain youthful NAD⁺ levels by supporting CD38 balance, while Luteolin provides additional antioxidant and photoprotective benefits that promote healthy cellular signaling and longevity.

EGCG (from Green Tea)

Epigallocatechin gallate (EGCG) supports cellular metabolism, stress resilience, and longevity pathways through its powerful antioxidant and signaling effects.
It complements other polyphenols in Rejuvenate  to provide broad-spectrum support for healthy senescence modulation and cellular integrity.

AstraGin® (Bioavailability Optimizer)

Derived from Astragalus membranaceus and Panax notoginseng, AstraGin® has been clinically shown to enhance nutrient absorption by upregulating key intestinal transporters. It also supports gut barrier integrity and immune homeostasis, amplifying the effectiveness of the entire formula.

Science-Backed Longevity Synergy

Rejuvenate integrates ten complementary mechanisms to help maintain healthy cellular function:

• Senolytic support to promote the natural clearance of aged cells*

• Autophagy induction for cellular recycling and renewal*

• Antioxidant defense to reduce oxidative burden*

• Mitochondrial support for energy and resilience*

• Inflammatory balance for systemic health and performance*

Together, these ingredients deliver comprehensive support for the biological systems most affected by time and stress—helping your cells feel younger, stronger, and more efficient.