DailyDIM+™ References

DIM (Diindolylmethane)

  •  Fares F, Azzam N, Appel B, et al. The potential efficacy of 3,3'-diindolylmethane in prevention of prostate cancer development. Eur J Cancer Prev. 2010 May;19(3):199-203. [PMID: 20010430
  •  Le HT, Schaldach CM, Firestone GL, et al. Plant-derived 3,3’-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells. J Biol Chem. 2003 Jun 6;278 (23): 21136-45. [PMID: 12665522]
  •  Rajoria S, Suriano R, George A, et al. Estrogen induced metastatic modulators MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in thyroid cancer. PLoS One. 2011 Jan 18;6(1):e15879. [PMID: 21267453]
  • Ahmad A, Sakr WA, Rahman KM. Anticancer properties of indole compounds: mechanism of apoptosis induction and role in chemotherapy. Curr Drug Targets.2010 Jun;11(6):652-66. [PMID: 20298156]
  • Rahman KW, Li Y, Wang Z, et al. Gene expression profiling revealed survivin as a target of 3,3'-diindolylmethane-induced cell growth inhibition and apoptosis in breast cancer cells. Cancer Res. 2006 May 1;66(9):4952-60. [PMID: 16651453]

Calcium-D-Glucarate

  •  Zółtaszek R, Hanausek M, Kiliańska ZM, et al. The biological role of D-glucaric acid and its derivatives: potential use in medicine [in Polish]. Postepy Hig Med Dosw (Online). 2008 Sep 5;62:451-62. [PMID: 18772850]
  •  Dwivedi C, Heck WJ, Downie AA, et al. Effect of calcium glucarate on beta-glucuronidase activity and glucarate content of certain vegetables and fruits. Biochem Med Metab Biol. 1990 Apr;43(2):83-92. [PMID: 2346674]
  • Calcium-D-glucarate. Altern Med Rev. 2002 Aug;7(4):336-39. [PMID: 12197785]
  •  Walaszek Z, Hanausek-Walaszek M, Minton JP, et al. Dietary glucarate as anti-promoter of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis. Carcinogenesis. 1986 Sep;7(9):1463-36. [PMID: 3091283]
  • Walaszek Z, Szemraj J, Narog M, et al. Metabolism, uptake, and excretion of a D-glucaric acid salt and its potential use in cancer prevention. Cancer Detect Prev. 1997;21(2):178-90. [PMID: 9101079]
  • Abou-Issa H, Moeschberger M, el-Masry W, et al. Relative efficacy of glucarate on the initiation and promotion phases of rat mammary carcinogenesis. Anticancer Res. 1995 May-Jun;15(3):805-10. [PMID: 7645962]
  • Singh J, Gupta KP. Calcium glucarate prevents tumor formation in mouse skin. Biomed Environ Sci. 2003 Mar;16(1):9-16. [PMID: 12747003]
  •  Saluk-Juszczak J, Olas B, Nowak P, et al. Protective effects of D-glucaro- 1,4-lactone against oxidative modifications in blood platelets. Nutr Metab Cardiovasc Dis. 2008 Jul;18(6):422-28. [PMID:17933501]
  • Olas B, Saluk-Juszczak J, Nowak P, et al. Protective effects of D-glucaro 1,4-lactone against oxidative/nitrative modifications of plasma proteins. Nutrition. 2007 Feb;23(2):164-71. [PMID: 17234507]
  • Kolodziejczyk J, Saluk-Juszczak J, Wachowicz B. In vitro study of the antioxidative properties of the glucose derivatives against oxidation of plasma components. J Physiol Biochem. 2011 Jun;67(2):175-83. [PMID: 21086198] 

Activated BroccoRaphanin™ (Broccoli Seed Extract + Myrosinase Enzyme)

  •  Fahey JW, Holtzclaw WD, Wehage SL, et al. PLoS One. 2015;10(11):e0140963. doi:10.1371/journal.pone.0140963
  •  Okunade O, Niranjan K, Ghawi SK, et al. Mol Nutr Food Res. 2018;62(18):e1700980. doi:10.1002/mnfr.201700980
  •  Egner PA, Chen JG, Wang JB, et al. Cancer Prev Res (Phila). 2011;4(3):384-395. doi:10.1158/1940-6207.CAPR-10-0296
  •  Boddupalli S, Mein JR, Lakkanna S, et al. Front Genet. 2012;3:7. doi:10.3389/fgene.2012.00007
  • Burmeister WP, Cottaz S, Rollin P, et al. J Biol Chem. 2000;275(50):39385-39393. doi:10.1074/jbc.M006796200
  • Vanduchova A, Anzenbacher P, Anzenbacherova E. J Med Food. 2019;22(2):121-126. doi:10.1089/jmf.2018.0024
  • Fahey JW, Kensler TW. Front Nutr. 2021;8:648788. doi:10.3389/fnut.2021.648788
  • Houghton CA, Fassett RG, Coombes JS. Nutr Rev. 2013;71(11):709-726. doi:10.1111/nure.12060
  • Yagishita Y, Fahey JW, Dinkova-Kostova AT, et al. Molecules. 2019;24(19):3593 doi:10.3390/molecules24193593

AstraGin®:

  • T.C. Chang, etc. Effect of Ginsenosides on Glucose Uptake in Human Caco-2 Cells Is Mediated through Altered Na Glucose Cotransporter 1 Expression. J. of Agric. and Food Chemistry. 2007, 55, 1993-1998. 
  • S.F. Huang, etc. Effect of Ginsenoside Rb1 on Glucose Uptake and Expression of Glucose Transporter in Animal Cells. University of Manitoba, Canada. April, 2010. 
  • S.Y. Lee, etc. Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway. Scientific Reports. Sept., 2017.