Brain Boost+ References

References:

Paraxanthine:

• Orrú M, Guitart X, Karcz-Kubicha M, et al. Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humans. Neuropharmacology. 2013;67:476-484. doi:10.1016/j.neuropharm.2012.11.029
• Yoo C, Xing D, Gonzalez D, et al. Acute Paraxanthine Ingestion Improves Cognition and Short-Term Memory and Helps Sustain Attention in a Double-Blind, Placebo-Controlled, Crossover Trial. Nutrients. 2021;13(11):3980. Published 2021 Nov 9. doi:10.3390/nu13
• Jäger, R.; Purpura, M.; Wells, S.D.; Liao, K.; Godavarthi, A. Paraxanthine Supplementation Increases Muscle Mass, Strength, and Endurance in Mice. Nutrients 2022, 14, 893. https://doi.org/10.3390/nu14040893
• Xing D, Yoo C, Gonzalez D, et al. Dose-Response of Paraxanthine on Cognitive Function: A Double Blind, Placebo Controlled, Crossover Trial. Nutrients. 2021;13(12):4478. Published 2021 Dec 15. doi:10.3390/nu13124478
• Szlapinski SK, Charrette A, Guthrie N, Hilmas CJ. Paraxanthine safety and comparison to caffeine. Front Toxicol. 2023 Feb 2;5:1117729. doi: 10.3389/ftox.2023.1117729. PMID: 36818692; PMCID: PMC9932512.

Alpha-GPC:

• Marcus L, Soileau J, Judge LW, Bellar D. Evaluation of the effects of two doses of alpha glycerylphosphorylcholine on physical and psychomotor performance. J Int Soc Sports Nutr. 2017;14:39. Published 2017 Oct 5. doi:10.1186/s12970-017-0196-5
• Ziegenfuss T, Landis J, Hofheins J. Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. J Int Soc Sports Nutr. 2008;5(Suppl 1):P15. Published 2008 Sep 17. d
• Bellar, D., LeBlanc, N.R. & Campbell, B. The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength. J Int Soc Sports Nutr12, 42 (2015). https://doi.org/10.1186/s12970-015-0103-x
• Tamura Y, Takata K, Matsubara K, Kataoka Y. Alpha-Glycerylphosphorylcholine Increases Motivation in Healthy Volunteers: A Single-Blind, Randomized, Placebo-Controlled Human Study. Nutrients. 2021;13(6):2091. Published 2021 Jun 18. doi:10.3390/nu13062091
• Zeisel SH, da Costa KA. Choline: an essential nutrient for public health. Nutr Rev. 2009;67(11):615-623. doi:10.1111/j.1753-4887.2009.00246.x

Lion’s Mane:

• Szućko-Kociuba I, Trzeciak-Ryczek A, Kupnicka P, Chlubek D. Neurotrophic and Neuroprotective Effects of Hericium erinaceus. Int J Mol Sci. 2023;24(21):15960. Published 2023 Nov 3. doi:10.3390/ijms242115960
• Gregory J, Vengalasetti YV, Bredesen DE, Rao RV. Neuroprotective Herbs for the Management of Alzheimer's Disease. Biomolecules. 2021;11(4):543. Published 2021 Apr 8. doi:10.3390/biom11040543
• Chong PS, Fung ML, Wong KH, Lim LW. Therapeutic Potential of Hericium erinaceusfor Depressive Disorder. Int J Mol Sci. 2019;21(1):163. Published 2019 Dec 25. doi:10.3390/ijms21010163

N-acetyl L-tyrosine (NALT)

• Bloemendaal M, Froböse MI, Wegman J, et al. Neuro-Cognitive Effects of Acute Tyrosine Administration on Reactive and Proactive Response Inhibition in Healthy Older Adults. eNeuro. 2018;5(2):ENEURO.0035-17.2018. Published 2018 Apr 30. doi:10.1523/ENEURO.00
• Steenbergen L, Sellaro R, Hommel B, Colzato LS. Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance. Neuropsychologia. 2015;69:50-55. Doi:10.1016/j.neuropsychologia.2015.01.022
• Colzato LS, de Haan AM, Hommel B. Food for creativity: tyrosine promotes deep thinking. Psychol Res. 2015;79(5):709-714. doi:10.1007/s00426-014-0610-4
• Institute of Medicine (US) Committee on Military Nutrition Research; Marriott BM, editor. Food Components to Enhance Performance: An Evaluation of Potential Performance-Enhancing Food Components for Operational Rations. Washington (DC): National Academies
• Thomas JR, Lockwood PA, Singh A, Deuster PA. Tyrosine improves working memory in a multitasking environment. Pharmacol Biochem Behav. 1999;64(3):495-500. doi:10.1016/s0091-3057(99)00094-5

L-Theanine:

• Anas Sohail A, Ortiz F, Varghese T, et al. The Cognitive-Enhancing Outcomes of Caffeine and L-theanine: A Systematic Review. Cureus. 2021;13(12):e20828. Published 2021 Dec 30. doi:10.7759/cureus.20828
• Owen GN, Parnell H, De Bruin EA, Rycroft JA. The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci. 2008;11(4):193-198. doi:10.1179/147683008X301513
• Bryan J. Psychological effects of dietary components of tea: caffeine and L-theanine. Nutr Rev. 2008;66(2):82-90. doi:10.1111/j.1753-4887.2007.00011.x