GlucoPrime™

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GlucoPrime™ is a next-generation metabolic support formula designed to support healthy glucose metabolism, insulin signaling, gut barrier function, and metabolic communication as part of a comprehensive approach to metabolic resilience and healthy aging.

Rather than focusing on a single pathway, GlucoPrime™ is formulated to support multiple interconnected systems involved in metabolic balance, including post-prandial glucose handling, fasting glucose support, gut–metabolic signaling, cellular energy pathways, and healthy inflammatory responses.

Why GlucoPrime™ Is Different

Healthy metabolic function reflects the coordinated activity of multiple biological systems, including:

• Post-prandial glucose handling

• Insulin signaling and cellular glucose uptake

• Gut barrier integrity and microbiome balance

• Inflammatory and oxidative tone

• Metabolic gene expression and cellular energy production

GlucoPrime™ is designed to support all of these systems simultaneously, helping promote metabolic steadiness, flexibility, and long-term resilience rather than targeting a single downstream outcome.

Featured Benefits:

• Supports healthy blood sugar and insulin sensitivity*

• Helps maintain balanced post-meal glucose responses*

• Promotes gut barrier integrity and mucin layer resilience*

• Supports healthy inflammatory and oxidative stress responses*

• Enhances carbohydrate tolerance and nutrient uptake pathways*

• Supports mitochondrial efficiency and cellular energy metabolism*

GlucoPrime™ is built as a systems-level metabolic support formula, where each ingredient plays a distinct, non-redundant role across glucose handling, gut integrity, metabolic signaling, and cellular energy pathways.

Eriogut™ Pro – 300 mg

Advanced Gut–Glucose–Incretin Axis Modulation

Eriogut™ Pro is a proprietary, clinically informed complex that integrates high-potency citrus flavonoids with a next-generation postbiotic to address metabolic health at its most influential control point: the gut–glucose signaling interface.

Unlike conventional glucose-support ingredients that act downstream in the bloodstream, Eriogut™ Pro works upstream in the gastrointestinal tract, where incretin signaling, barrier integrity, and inflammatory tone are first established.

Eriogut™ Pro is composed of:

• Citrus Flavonoid Blend
  (>70% Eriocitrin from Citrus limon fruit, plus Hesperidin)

• PoZibio® Heat-Treated Lacticaseibacillus paracasei D3.5

Each component is individually supported by research—but it is their synergistic integration that makes Eriogut™ Pro uniquely powerful.

High-Potency Citrus Flavonoids (>70% Eriocitrin + Hesperidin)

Incretin, Antioxidant & Metabolic Signaling Support

Eriocitrin is one of the most potent and bioactive citrus flavonoids studied in the context of metabolic health. In human and preclinical research, eriocitrin-rich citrus extracts have been shown to support:

• GLP-1–related incretin signaling, a key regulator of post-meal glucose handling

• Healthy insulin sensitivity and glucose uptake pathways

• Antioxidant defenses, including reductions in oxidative stress markers

• Healthy inflammatory balance, particularly in metabolically active tissues

Hesperidin complements eriocitrin by supporting:

• Endothelial and microvascular function

• Inflammatory balance within a healthy range

• Additional α-glucosidase–related carbohydrate metabolism pathways

PoZibio® is a heat-inactivated postbiotic originally developed through research at Wake Forest University and supported by NIH and Department of Defense funding.

Unlike live probiotics, PoZibio® delivers its benefits through structural cell wall components, particularly lipoteichoic acid (LTA), which interact directly with intestinal immune and epithelial signaling pathways.

Brightseed® BioMetaControl™ (NCT + NFT) – 120 mg

Targeted Nutrigenomic Support for Core Metabolic Signaling Pathways

BioMetaControl™ is a precision-discovered bioactive complex featuring N-trans-caffeoyltyramine (NCT) and N-trans-feruloyltyramine (NFT)—naturally occurring plant compounds identified using Brightseed’s AI-driven Forager® platform.

These bioactives have been studied for their ability to support HNF4α-associated metabolic signaling, a central regulatory pathway involved in maintaining healthy glucose and lipid metabolism. 

Within GlucoPrime™, BioMetaControl™ provides upstream nutrigenomic support, helping maintain healthy metabolic signaling at the level of gene expression rather than forcing short-term changes in blood glucose.

By supporting HNF4α-related pathways, BioMetaControl™ complements gut-level glucose moderation (Reducose®), cellular glucose utilization (dihydroberberine and chromium), and mitochondrial support (Naturalin®), contributing to a coordinated, systems-level approach to metabolic resilience.

Reducose® (White Mulberry Leaf Extract, standardized to 5% DNJ) – 250 mg

Post-Meal Glucose Moderation & Carbohydrate Tolerance

Reducose® is a patented mulberry leaf extract standardized for 1-deoxynojirimycin (DNJ), a naturally occurring compound that supports healthy post-prandial glucose handling.

Unlike ingredients that influence insulin secretion, Reducose® works locally in the small intestine, where it supports carbohydrate metabolism by slowing the enzymatic breakdown of starches and sugars. This helps moderate the rate at which glucose enters the bloodstream after meals.

Naturalin® (Highly Soluble Ellagic Acid with Choline) – 100 mg

Cellular Energy, Liver & Antioxidant Support

Naturalin® is a patented, highly soluble form of ellagic acid bound to choline, designed to overcome the poor absorption of conventional ellagic acid and support consistent biological activity. This advanced complex supports healthy antioxidant and redox balance, liver metabolic pathways, and mitochondrial efficiency—foundational systems involved in cellular energy production and metabolic resilience. By supporting these core processes, Naturalin® helps create the metabolic environment needed for efficient glucose handling and overall metabolic balance.

GlucoVantage® (Dihydroberberine) – 200 mg

Cellular Glucose Uptake & Metabolic Signaling Support

GlucoVantage® is a highly bioavailable form of dihydroberberine (DHB), the metabolite that conventional berberine must first be converted into before absorption, allowing for more efficient metabolic support at lower doses and with improved gastrointestinal tolerability. DHB supports AMPK-related metabolic signaling, healthy cellular glucose uptake, and lipid and energy metabolism—key processes involved in how efficiently cells utilize glucose between meals, not just after eating. Within GlucoPrime™, GlucoVantage® functions as the intracellular metabolic signaling component, complementing gut-level glucose moderation by supporting cellular energy use and metabolic efficiency.

Chromium (as Chromium Picolinate) – 400 mcg

Insulin Signaling & Glucose Utilization Support

Chromium is an essential trace mineral involved in carbohydrate and lipid metabolism. Chromium picolinate is one of the most studied and bioavailable forms used to support normal insulin signaling and glucose utilization.

GlucoPrime™ is a metabolic support supplement designed to support healthy blood sugar balance, insulin signaling, and gut–metabolic communication. This systems-based formula addresses key contributors to metabolic resilience, including post-meal glucose handling, cellular glucose utilization, gut barrier integrity, nutrigenomic metabolic signaling, and mitochondrial energy pathways.

CONTAINS: MILK (used in the fermentation process of BioMetaControl™)

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