Nuritas
The Problem with How the Supplement Industry Discovers Ingredients
Walk down any supplement aisle and you will likely find the same ingredients that have existed for decades. Whey protein. Creatine. Melatonin. Magnesium. They work — but they are old. Traditional bioactive ingredient discovery requires manually screening candidate compounds one by one in a lab, a process that takes decades and costs hundreds of millions of dollars. Most companies simply cannot afford it, which is why the industry keeps reformulating the same raw materials under different names.
At Healthgevity, we believe practitioners and their patients deserve better than that. It is why one of our most important innovation partnerships is with Nuritas — a Dublin-based biotechnology company that has fundamentally changed how bioactive ingredients are discovered, validated, and brought to market.
Who Is Nuritas?
Nuritas uses artificial intelligence to unlock peptides hidden inside plants and natural food sources — peptides that would never be found through traditional screening methods because the sheer number of candidates makes manual testing impossible.
A single apple contains more distinct molecules than all the social media data generated since the internet began. Identifying which of those molecules produce meaningful, reproducible health effects by hand would require centuries and an unlimited budget. Nuritas solves this through their proprietary AI platform: the Magnifier™.
The Magnifier™ Platform
The Magnifier™ integrates machine learning, proteomics, peptidomics, and molecular biology to screen billions of peptide sequences and predict — with extraordinary precision — which candidates will produce meaningful biological effects. It then validates those candidates through rigorous human clinical trials before any ingredient reaches a formulation.
The result is an 80% success rate from peptide discovery to clinical efficacy — a benchmark that reached 100% across Nuritas's last five commercialized ingredients. No traditional ingredient development process in the nutraceutical industry comes close to this standard.
This is not marketing science. This is biotech-grade clinical development applied to practitioner nutrition.
"These are not protein fragments. They are cell-signaling molecules — designed by nature, unlocked by AI — that communicate directly with biological pathways to modulate gene expression, drive protein synthesis, and support the body's own repair systems."
The Three-Phase Discovery Process
Phase 1 — AI Discovery: The Magnifier™ screens billions of plant-derived peptide sequences, identifying candidates with the structural profile to interact with specific biological targets — mTOR pathways, myostatin suppression, cortisol modulation, collagen synthesis signaling, and more.
Phase 2 — Preclinical Validation: Shortlisted peptides undergo rigorous in vitro and preclinical biology testing to confirm mechanism of action and establish safety parameters before any human exposure.
Phase 3 — Human Clinical Trials: Every commercialized Nuritas ingredient is validated through randomized, double-blind, placebo-controlled human clinical trials — the gold standard of evidence-based medicine. Results are published in peer-reviewed journals including The Journal of Nutrition and Nutrients.
The Nuritas Ingredients Inside Healthgevity Formulas
Healthgevity is the only practitioner-channel company worldwide with active access to the full Nuritas SmartPeptides™ portfolio in finished formulas. Here is the science behind each ingredient we use — and why we chose it.
PeptiStrong® — Muscle Longevity & Recovery
Source: Fava bean (Vicia faba) protein hydrolysate
PeptiStrong® is the most clinically studied cell-signaling peptide ingredient for muscle health ever developed. Identified within fava bean protein, it contains specific peptide sequences that target intracellular signaling pathways governing muscle protein synthesis, ATP energy production, and myostatin regulation — the key biological levers of muscle mass, recovery, and performance.
Unlike traditional protein supplementation, which relies on raw amino acid content, PeptiStrong® operates upstream — activating the cellular machinery that drives muscle adaptation rather than simply supplying substrate. At a clinical dose of just 2.4g/day, it outperformed milk protein in muscle protein synthesis rate during recovery in a Maastricht University trial published in The Journal of Nutrition.
Clinical Evidence — 3 Randomized Controlled Trials:
- 148% increase in strength recovery versus placebo
- 54% increase in muscle energy at 72 hours post-exercise
- 47% reduction in muscle fatigue
- 17% increase in overall strength versus placebo
- Significant suppression of myostatin — a primary inhibitor of muscle growth
- Outperformed milk protein in muscle protein synthesis rate during recovery
Found in: Longevity · Prime Strength
PeptiSleep™ — Sleep Architecture & Cortisol Modulation
Source: Brown rice (Oryza sativa) protein · Melatonin-free
PeptiSleep™ is the first AI-discovered peptide ingredient clinically validated to improve all four dimensions of sleep quality simultaneously. Where conventional sleep ingredients like melatonin address only sleep onset by mimicking a hormonal signal, PeptiSleep™ targets elevated cortisol — one of the primary root causes of fragmented, non-restorative sleep — through peptide-mediated modulation of the HPA-axis stress response.
This mechanism allows PeptiSleep™ to improve not just the ability to fall asleep, but the quality, depth, and continuity of sleep — and critically, next-day cognitive function and alertness — without the morning grogginess associated with sedative-based sleep aids. Results are measurable via wearable devices tracking HRV, sleep stages, and readiness scores.
Clinical Evidence — LSEQ Randomized Controlled Trial:
- 10.2-point composite improvement across all four LSEQ domains (a 1-point improvement is considered clinically significant)
- +38 minutes of additional sleep per night on average
- All four LSEQ domains improved: ease of getting to sleep, quality of sleep, behavior following wakefulness, alertness on waking
- No melatonin. No dependency. No next-day grogginess.
Found in: SLEEPgevity
PeptiYouth® — Skin Aging & Collagen Signaling
Source: Plant-derived peptide complex · Oral and topical delivery
PeptiYouth® is the world's first clinically tested anti-aging peptide discovered through AI. It addresses skin aging at the cellular signaling level — activating endogenous collagen synthesis pathways to target five measurable signs of aging simultaneously: deep wrinkle depth, skin roughness, pore appearance, skin tone, and collagen architecture.
Clinical Evidence — 28-Day RCT (n=40, double-blind, placebo-controlled):
- Significant reduction in wrinkle depth
- Measurable decrease in skin roughness
- Reduction in skin inflammation biomarkers
- Increase in collagen production markers
- Five measurable signs of skin aging addressed simultaneously
Found in: FACEgevity
PeptiPump® — Vascular Performance & Endothelial Support
Source: Plant-derived peptide complex · Oral delivery
PeptiPump® is Nuritas's most recently commercialized ingredient, targeting vascular performance, nitric oxide-mediated vasodilation, and endothelial resilience through precision peptide signaling. Developed for clinicians working with patients on cardiovascular resilience, circulatory performance, and exercise capacity, it supports healthy vascular flow, endothelial function, glycocalyx integrity, and muscle oxygenation during physical activity.
Key Biological Targets:
- Nitric oxide-mediated vasodilation and healthy vascular signaling
- Endothelial function and glycocalyx integrity
- Healthy vascular flow and muscle oxygenation during exercise
- Balanced circulatory dynamics and cardiometabolic wellness support
Found in: Prime Strength · Cardio NAD+
The Peer-Reviewed Science
Every Nuritas ingredient in the Healthgevity portfolio is backed by published, peer-reviewed human clinical research. Key publications include:
- Kerr, A. et al. "Improved Strength Recovery and Reduced Fatigue with Suppressed Plasma Myostatin Following Supplementation of a Vicia Faba Hydrolysate, in a Healthy Male Population." Nutrients, 2023.
- Maastricht University: "PeptiStrong vs. milk protein — muscle mass and protein synthesis during recovery." The Journal of Nutrition, January 2023.
- PeptiSleep™ LSEQ randomized controlled trial. All four domains of sleep quality improved with a composite 10.2-point gain. Australia, 2025.
- PeptiYouth® 28-day double-blind, placebo-controlled RCT (n=40): collagen synthesis and skin aging biomarkers.
Nuritas-Powered Products in the Healthgevity Portfolio
| Product | Nuritas Ingredient(s) | Primary Clinical Target |
|---|---|---|
| Prime Strength | PeptiStrong® + PeptiPump® | Muscle longevity, recovery, vascular performance |
| Longevity | PeptiStrong® | Anabolic signaling, muscle preservation, healthspan |
| SLEEPgevity | PeptiSleep™ | Sleep architecture, cortisol modulation, recovery |
| FACEgevity | PeptiYouth® | Skin aging, collagen synthesis, cellular renewal |
| Cardio NAD+ | PeptiPump® | Vascular performance, endothelial support, circulatory health |
Healthgevity. Powered by the Future of Biological Science.
We don't source ingredients because they're popular. We source them because the science demands it. Our partnership with Nuritas reflects the same standard we apply across our entire portfolio: first-to-market, clinically validated, and accessible only through the practitioner channel.
Apply for a Practitioner Account →
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. For Healthcare Professional Use Only.